Tuesday, October 20, 2009
Doctors' conflicts of interest can harm your health - Part 1 of 3
From my experience, most doctors rely on three primary sources of new information: scientific journals (such as the one I edit, American Family Physician), medical conferences, and information from pharmaceutical company representatives (or "drug reps"). You would probably expect information from the latter to be biased, since drug reps are trained to sell drugs, not to do what's best for patients. Organizations such as No Free Lunch have established that physicians who allow drug reps access to their practices to distribute free drug samples, meals, and other promotional products (such as pens, prescription pads, etc.) often end up prescribing expensive or second-line drugs to patients instead of the drugs recommended by national guidelines. Led by the American Medical Student Association, many medical schools have now established strict rules governing interactions between students, faculty, and drug companies.
But pens and drug samples are only the most visible ways that drug companies push their products. Recently, it has become obvious that an entire hidden industry of drug-company funded "ghostwriters" has been publishing articles in medical journals for years. A study by the editors of the Journal of the American Medical Assocation found that from 2-11 percent of articles published in 2008 in six major journals (including the New England Journal of Medicine) were actually written by people who were not named as authors. While the study could not establish that these particular ghostwriters had been directly financed by drug companies, the practice of writing up a scientific study and then recruiting a lead author (usually an academic physician under pressure to "publish or perish") has been well-documented in the case of previous "blockbuster" drugs that were taken by millions of patients for common conditions but later turned out to have dangerous or fatal side effects, including Wyeth's Prempro and Merck's Vioxx.
In an upcoming post, I'll discuss recent efforts by medical journals to save their scientific credibility from the "dirty little secret" of drug company influences.
Thursday, October 15, 2009
Post call: resident duty hour regs in perspective
"Post call" is shorthand for being at work the day after having spent the entire previous day and night working. While this sort of situation isn't unique to medicine (for example, attorneys in some specialities pull similar sleep-deprived work shifts early in their careers), it's probably the best known, thanks to medical-themed television shows such as "ER." In the days when medical interns lived at the hospital and were almost exclusively unmarried men, being post call every other day and regularly working more than 100 hours per week was not at all unusual.
Fortunately, by the time I did my family medicine residency (2001-04), matters had improved significantly. Although the Accreditation Council for Graduate Medical Education didn't mandate that programs limit residents to 30-hour shifts and an 80-hour work week until 2003, my program made the change in my second year. We all got more sleep, and I don't feel that quality of care suffered - what experiences I may have missed out on by not stumbling around the wards on a post call afternoon, I made up for by being awake to read more about the patients I was managing. So it strikes me as odd that serious physicians are still debating whether enacting the regulations was the right move - as if the benefits of more sleep to residents can be measured scientifically in any complete and objective way.
In 1997, Vancouver resident Rachel Rose, the author of two books of poetry (most recently, 2005's Notes on Arrival and Departure) published in JAMA what has long been my favorite evocative description of caring for a soul mate who's post call.
**
PostcallPostcall you come home diminished, wan, your hands
Faltering at the lock. You feel a need to tell me
Each patient’s history before you sleep,
The progress of each malignancy, the way the family
Spoke to you, the suffering that makes death a release.
I understand. But I wait for you, Isabelle,
Not your stories of the progress of the dying.
I lead you to bed like a child, almost crying
With fatigue and despair these anaemic mornings
When you have donated all your strength
And then come home to me, stricken, empty
And grateful for the smallest gesture of tenderness,
My easing your heel from your boot as you undress,
Holding you while you try to reclaim your membership
As one who sleeps. Your limbs twitch
Like a dog’s, hurrying into dreams, your lips
Part with sighs. I soothe you with my weight,
Whisper about the snow piling up outside.
Your eyes close, it’s late afternoon, slow repose
Beckons. But even in dreams your fingers pleat the quilt
As if gathering the flesh of an arm before a shot.
I understand. Accountability never leaves your hands.
– Rachel Rose
Saturday, October 10, 2009
Mental health care: a Bellevue success story
**
CONGRATULATIONS FROM THE COMMUNITY OF TWENTY EAST
I hardly recognized him. How changed
He appeared from that combative, demanding
Patient I knew on those 90-degree days in July!
Then he had been overflowing with suggestions
For his treatment – use this painkiller, not that one –
Living up to the secondhand stories of his terrorizing
Orderlies at Beth Israel. “Can’t anybody see a doctor here?”
Loitering at the nurses’ station, demanding his methadone
On the clock. At war with Sanders over the morality of the unit.
We groaned. Later, dominating therapy groups, he puffed up
With pride at his “progress.” I shied away, leaving him
In the spotlight one last time for others to examine.
Antisocial personality disorder, the attending pronounced.
Sense of entitlement. Which made me wince.
The man just needed a stage. Those final days,
I watched him play spades with the pretty volunteer,
A new man. Praising me to the skies, his Good Doctor.
I saw him on the sidewalk this morning, with headphones
And shiny Giants jacket, inhaling the crisp autumn air.
He shook my hand, wished me the best.
Thursday, October 8, 2009
Medication errors and patient safety
Taking doses that are too large, or taking correct doses too frequently, can cause serious and even fatal side effects. An advisory committee to the Food and Drug Administration recently voted to lower the maximum daily dose of Tylenol due to evidence that many adults sustain liver damage by inadvertently taking too much. On the other hand, inadequate dosing of medications can result in conditions such as epilepsy, diabetes, and high blood pressure being poorly controlled.
Patients may take medicines improperly because their doctor gives inadequate oral or written instructions. More prescription medications also may make errors more likely. In a 2006 study published in the Annals of Internal Medicine, Dr. Terry Davis and colleagues examined the relationship between literacy levels and a patient's understanding of common prescription drug labels.
In this study, 395 English-speaking adults were recruited from 3 primary care clinics' waiting rooms. They were shown 5 labeled prescription medicine bottles and asked to describe how they would take each medication, including the number of pills to be taken in a day. The interview concluded with a health literacy assessment to determine the patient's literacy level: low (sixth grade and lower), marginal (seventh to eighth grade), or adequate (ninth grade and higher).
Out of 1,975 responses, 374 were incorrect. Most incorrect responses were dosage errors (51.8 percent) and dose frequency errors (28.2 percent). A few patients were unable to find the instructions on the label (5.8 percent) or admitted to being unable to read (3.2 percent). Incorrect responses were strongly associated with low and marginal literacy levels, and the risk of an incorrect response increased with more medications used. Surprisingly, many patients who read the instructions correctly still counted out an incorrect number of pills.
This study reinforced my longstanding (but unfortunately time-consuming) practice of asking all of my patients who take regular medications to bring in their pill bottles at every visit so we can go over how to take each one properly. Quite often, I'd find that another doctor had added or changed a prescription without telling me about it, often leading the patient to take two different medicines for the same condition. Without a single physician coordinating care, medication errors become almost inevitable. So how might health reform address this problem? Stay tuned.
Monday, October 5, 2009
Why "patient centered" health care isn't the norm
When I did my medical training a decade ago, it often seemed to me that medical students were encouraged to depersonalize patients and not listen to their concerns. During my surgical and medical rotations, a patient with stomach pain became "the abdomen in room 6," and the patient with a rare or difficult-to-diagnose illness became a "great case." There was a distinct pecking order within the prestigious academic hospitals where I did my clinical rotations - attending physicians at the top, followed by fellows, residents, nurses, students and other trainees, and finally, at the very bottom, the patients themselves. We took for granted that on the basis of years of studying medicine, we knew what was best for patients, and the few who questioned whether our care was actually making their health better were quickly labeled as "difficult" or "non-compliant."
National patient safety advocate Sorrel King, whose one-year old daughter died in Johns Hopkins Children's Center due to preventable medical errors, writes in her poignant 2009 memoir Josie's Story that being in awe of the technical skills of her daughter's physicians made her reluctant to challenge questionable medical decisions until it was too late. One of the reforms that she and her foundation have encouraged hospitals to adopt is the development of rapid response teams that could be triggered by anyone in the medical hierarchy who had concerns about a patient's condition, including - and especially - patients and family members.
But you don't have to set foot inside a hospital to know that we have a long way to go to get to patient centered care. It's typical in most parts of the U.S. to have to wait months to consult a family doctor about a non-acute problem. When you finally arrive at the office, you often aren't ushered back to an examining room until half an hour or more after your scheduled appointment time, then have to wait some more to actually see the doctor, who may spend five minutes or less with you before he or she is racing off to the next patient. (I'm happy to say that not every practice I've worked at fits this description - for an example of how electronic medical records and "advanced access" scheduling can greatly reduce such inconveniences, see the website of the one of the premier primary care practices in the DC Metro area.)
In future posts, I'll write more about a few important topics that I've only touched on here: improving patient safety, shared decision making, and practice transformation, including the patient centered (there's that term again!) medical home.
Thursday, October 1, 2009
Taking the Pulse of primary care medicine
Paul Gross, MD, an academic family physician at Montefiore Medical Center in New York and editor of the online magazine Pulse: voices from the heart of medicine, recently wrote a poignant piece about the challenges of family doctoring in the context of 15-minute (or shorter) appointment slots. In "Late Again," Dr. Gross observes:
"The joy of primary care is also its curse. With each patient, I have to keep track of everything--the trivial and life-threatening, the physical and mental, the acute, the chronic and the preventive. And try as I might, I simply don't have enough time. ... My colleagues and I are often still seeing our morning patients at 1:00, when our afternoon session is supposed to begin. Lunch hour? Wouldn't it be nice. And I have it easy. One hears of offices scheduling patients every ten minutes--every ten minutes!--and doctors "seeing" fifty patients a day.
Doctors talk of running on a hamster wheel. Patients complain that their doctors seem distracted, don't take the time to listen, and run late--as I routinely do. Am I a bad doctor--disorganized and inefficient? Or maybe I'm doomed to fall short as I bump up against powerful economic forces--the 'do-more-with-less' pressures that make medical administrators everywhere create schedules like mine, designed to bring in enough money to keep health centers afloat but which end up hustling me and my patients along at an impossible pace. As a nation, we are now trying to fix our foundering healthcare system. Before we set new rules in place, shouldn't we first ask this basic question: how much time is actually required to see a patient?"
As all physicians know, time spent with patients doesn't include time spent documenting visits, reviewing test results, making referrals, filling out administrative paperwork, et cetera. A 2007 study in the Annals of Internal Medicine estimated that doctors in an academic geriatric practice who saw only 14 patients per day (most docs in private practice see 30 to 40) spent nearly 8 hours per week on these non-reimbursed tasks. This reality has led some solo family physicians to adopt a no-frills practice model that relies on few (or no) staff, leading to lower overhead costs and more time to see patients. Unfortunately, more time per patient means fewer patients per day, so such a model applied nationwide would require training even more family physicians, in addition to the ones we already don't have.






